Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGI2Leucine rich repeat LGI family member 2. (497 aa)    
Predicted Functional Partners:
ADAM22
ADAM metallopeptidase domain 22.
     
 0.944
ADAM23
ADAM metallopeptidase domain 23.
     
 0.940
ADAM11
ADAM metallopeptidase domain 11.
     
 0.860
ZDBF2
DBF4-type domain-containing protein.
     
 0.594
FBXL17
Uncharacterized protein.
   
 
 0.558
FAM214A
Family with sequence similarity 214 member A.
      
 0.546
SMOC1
SPARC related modular calcium binding 1.
      
 0.538
HAUS3
HAUS augmin like complex subunit 3.
      
 0.536
NXPH3
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.519
ZC3H6
Zinc finger CCCH-type containing 6.
      
 0.511
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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