Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SLC40A1Solute carrier family 40 member 1. (777 aa)    
Predicted Functional Partners:
HAMP
Hepcidin antimicrobial peptide.
    
 0.994
HEPH
Hephaestin; Belongs to the multicopper oxidase family.
    
 0.979
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
    
 0.963
SLC11A2
Solute carrier family 11 member 2.
      
 0.882
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
    
 0.825
TFRC
Transferrin receptor.
      
 0.814
FTH1
Ferritin heavy chain; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
      
 0.795
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
      
 0.795
HJV
Hemojuvelin BMP co-receptor.
      
 0.788
FTL
Ferritin light chain; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity); Belongs to the ferritin family.
      
 0.783
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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