Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RELREL proto-oncogene, NF-kB subunit. (592 aa)    
Predicted Functional Partners:
NFKB1
Nuclear factor kappa B subunit 1.
   
0.997
NFKB2
Nuclear factor kappa B subunit 2.
   
0.995
NFKBIA
NFKB inhibitor alpha.
   
 0.993
NFKBIE
NFKB inhibitor epsilon.
   
 0.991
NFKBIB
NFKB inhibitor beta.
   
 0.990
ENSOCUP00000046340
RHD domain-containing protein.
    
 
 0.959
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.954
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.950
STAT3
Signal transducer and activator of transcription.
   
 0.943
TBK1
TANK binding kinase 1.
   
 0.938
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (36%) [HD]