SULT1E1 protein (Oryctolagus cuniculus) - STRING interaction network

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SULT1E1

Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)

Predicted Functional Partners:

HSD17B2

0.935

HSD17B1

0.929

CYP19A1

0.925

UGT1

0.925

CYP1A1

0.912

HSD17B8

0.903

HSD17B12

0.879

CYP3A6

0.873

CYP1A2

0.843

UGT2C1

0.828

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP19A1	CYP1A1	ENSOCUP00000010591	ENSOCUP00000015239	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	0.918
CYP19A1	CYP1A2	ENSOCUP00000010591	ENSOCUP00000008665	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...]	0.845
CYP19A1	CYP3A6	ENSOCUP00000010591	ENSOCUP00000034396	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450 3A6; Exhibits progesterone 6 beta-hydroxylase activity.	0.893
CYP19A1	HSD17B1	ENSOCUP00000010591	ENSOCUP00000020404	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Uncharacterized protein.	0.974
CYP19A1	HSD17B12	ENSOCUP00000010591	ENSOCUP00000016136	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.932
CYP19A1	HSD17B2	ENSOCUP00000010591	ENSOCUP00000014316	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.947
CYP19A1	HSD17B8	ENSOCUP00000010591	ENSOCUP00000017884	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Hydroxysteroid 17-beta dehydrogenase 8.	0.894
CYP19A1	SULT1E1	ENSOCUP00000010591	ENSOCUP00000004352	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.925
CYP19A1	UGT1	ENSOCUP00000010591	ENSOCUP00000033104	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	UDP-glucuronosyltransferase 1-4; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds; Belongs to the UDP-glycosyltransferase family.	0.870
CYP19A1	UGT2C1	ENSOCUP00000010591	ENSOCUP00000023419	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	UDP-glucuronosyltransferase 2C1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.895
CYP1A1	CYP19A1	ENSOCUP00000015239	ENSOCUP00000010591	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.918
CYP1A1	CYP1A2	ENSOCUP00000015239	ENSOCUP00000008665	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...]	0.851
CYP1A1	CYP3A6	ENSOCUP00000015239	ENSOCUP00000034396	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Cytochrome P450 3A6; Exhibits progesterone 6 beta-hydroxylase activity.	0.932
CYP1A1	HSD17B1	ENSOCUP00000015239	ENSOCUP00000020404	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Uncharacterized protein.	0.895
CYP1A1	HSD17B12	ENSOCUP00000015239	ENSOCUP00000016136	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.864
CYP1A1	HSD17B2	ENSOCUP00000015239	ENSOCUP00000014316	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.899
CYP1A1	HSD17B8	ENSOCUP00000015239	ENSOCUP00000017884	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Hydroxysteroid 17-beta dehydrogenase 8.	0.881
CYP1A1	SULT1E1	ENSOCUP00000015239	ENSOCUP00000004352	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.912
CYP1A1	UGT1	ENSOCUP00000015239	ENSOCUP00000033104	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	UDP-glucuronosyltransferase 1-4; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds; Belongs to the UDP-glycosyltransferase family.	0.942
CYP1A1	UGT2C1	ENSOCUP00000015239	ENSOCUP00000023419	Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]	UDP-glucuronosyltransferase 2C1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.	0.908