Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)    
Predicted Functional Partners:
ADA
Adenosine deaminase.
  
 
 0.981
ADK
Adenosine kinase.
  
 
 0.969
GDA
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
 
 0.964
NMRK1
Uncharacterized protein.
  
 0.944
ENSOCUP00000041459
Uncharacterized protein.
  
 
 0.931
G1U654_RABIT
NAPRTase_C domain-containing protein.
    
 0.923
DCK
Deoxycytidine kinase.
     
 0.921
NT5C2
Uncharacterized protein.
   
 
 0.909
XDH
Uncharacterized protein.
   
 
 0.906
NT5C
5', 3'-nucleotidase, cytosolic.
     
 0.892
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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