STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D8BTBC1 domain family member 8B. (1118 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 
 0.943
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
   
 
 0.839
GAPVD1
GTPase activating protein and VPS9 domains 1.
   
 
 0.831
ERI2
ERI1 exoribonuclease family member 2.
   
  
 0.744
TBC1D20
TBC1 domain family member 20.
      
 0.675
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 
  0.656
RAB25
Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). ECO:0000250|UniProtKB:P57735, ECO:0000250|UniProtKB:Q9WTL2,; Belongs to the small GTPase superfamily. Rab family.
    
 0.645
TBCA-2
Tubulin-specific chaperone A; Belongs to the TBCA family.
      
 0.629
TBCA
Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
      
 0.629
TBC1D23
TBC1 domain family member 23.
   
  
 0.605
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.