WRNIP1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

WRNIP1

WRN helicase interacting protein 1. (445 aa)

Predicted Functional Partners:

WRN

0.936

RAD18

0.881

PCNA

0.858

BLM

0.844

G1TXZ4_RABIT

0.841

DNA2

0.810

UBASH3B

0.790

POLD2

0.761

ZRANB3

0.727

HLTF

0.710

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	DNA2	ENSOCUP00000012010	ENSOCUP00000024846	BLM RecQ like helicase.	DNA replication helicase/nuclease 2.	0.975
BLM	HLTF	ENSOCUP00000012010	ENSOCUP00000047915	BLM RecQ like helicase.	Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Mediates repression by c-Rel through a DNA-looping mechanism. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination o [...]	0.703
BLM	PCNA	ENSOCUP00000012010	ENSOCUP00000003512	BLM RecQ like helicase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.886
BLM	POLD2	ENSOCUP00000012010	ENSOCUP00000012844	BLM RecQ like helicase.	DNA polymerase delta 2, accessory subunit.	0.607
BLM	RAD18	ENSOCUP00000012010	ENSOCUP00000029275	BLM RecQ like helicase.	Uncharacterized protein.	0.841
BLM	WRN	ENSOCUP00000012010	ENSOCUP00000010872	BLM RecQ like helicase.	WRN RecQ like helicase.	0.720
BLM	WRNIP1	ENSOCUP00000012010	ENSOCUP00000004401	BLM RecQ like helicase.	WRN helicase interacting protein 1.	0.844
DNA2	BLM	ENSOCUP00000024846	ENSOCUP00000012010	DNA replication helicase/nuclease 2.	BLM RecQ like helicase.	0.975
DNA2	HLTF	ENSOCUP00000024846	ENSOCUP00000047915	DNA replication helicase/nuclease 2.	Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Mediates repression by c-Rel through a DNA-looping mechanism. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination o [...]	0.742
DNA2	PCNA	ENSOCUP00000024846	ENSOCUP00000003512	DNA replication helicase/nuclease 2.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.924
DNA2	POLD2	ENSOCUP00000024846	ENSOCUP00000012844	DNA replication helicase/nuclease 2.	DNA polymerase delta 2, accessory subunit.	0.869
DNA2	RAD18	ENSOCUP00000024846	ENSOCUP00000029275	DNA replication helicase/nuclease 2.	Uncharacterized protein.	0.529
DNA2	WRN	ENSOCUP00000024846	ENSOCUP00000010872	DNA replication helicase/nuclease 2.	WRN RecQ like helicase.	0.997
DNA2	WRNIP1	ENSOCUP00000024846	ENSOCUP00000004401	DNA replication helicase/nuclease 2.	WRN helicase interacting protein 1.	0.810
DNA2	ZRANB3	ENSOCUP00000024846	ENSOCUP00000038477	DNA replication helicase/nuclease 2.	Zinc finger RANBP2-type containing 3.	0.812
G1TXZ4_RABIT	WRNIP1	ENSOCUP00000021952	ENSOCUP00000004401	Uncharacterized protein.	WRN helicase interacting protein 1.	0.841
HLTF	BLM	ENSOCUP00000047915	ENSOCUP00000012010	Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Mediates repression by c-Rel through a DNA-looping mechanism. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination o [...]	BLM RecQ like helicase.	0.703
HLTF	DNA2	ENSOCUP00000047915	ENSOCUP00000024846	Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Mediates repression by c-Rel through a DNA-looping mechanism. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination o [...]	DNA replication helicase/nuclease 2.	0.742
HLTF	PCNA	ENSOCUP00000047915	ENSOCUP00000003512	Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Mediates repression by c-Rel through a DNA-looping mechanism. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination o [...]	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.989
HLTF	RAD18	ENSOCUP00000047915	ENSOCUP00000029275	Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Mediates repression by c-Rel through a DNA-looping mechanism. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination o [...]	Uncharacterized protein.	0.982