STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WRNIP1WRN helicase interacting protein 1. (445 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
  
 
 0.971
RAD18
Uncharacterized protein.
   
 
 0.887
FBH1
F-box DNA helicase 1.
    
 
 0.781
BLM
BLM RecQ like helicase.
  
 
 0.773
ZRANB3
Zinc finger RANBP2-type containing 3.
  
 
 0.745
POLD2
DNA polymerase delta 2, accessory subunit.
    
 
 0.734
DNA2
DNA replication helicase/nuclease 2.
    
 
 0.733
RECQL5
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 
 0.697
EXD2
Exonuclease 3'-5' domain containing 2.
    
 
 0.680
HLTF
Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Mediates repression by c-Rel through a DNA-looping mechanism. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination o [...]
  
 
 0.653
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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