Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STK10Serine/threonine kinase 10. (970 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
    
 0.772
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
     
  0.732
CCNB2
Cyclin B2; Belongs to the cyclin family.
     
 0.602
CCNB1
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
     
 0.602
RDX
Radixin.
    
 
 0.519
EZR
Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).
    
 
 0.516
FCHSD1
FCH and double SH3 domains 1.
      
 0.508
PKN2
Protein kinase N2.
   
 
 0.508
CAMK4
Protein kinase domain-containing protein.
    
   0.507
MSN
FERM domain-containing protein.
   
 
 0.504
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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