STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOPXHomeobox domain-containing protein. (73 aa)    
Predicted Functional Partners:
HDAC2
Histone deacetylase 2.
    
 
 0.794
LRIG1
Leucine rich repeats and immunoglobulin like domains 1.
    
 
 0.784
SFTPC
Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
      
 0.772
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 
 0.763
BMI1
RING-type domain-containing protein.
      
 0.703
FAM107A
Family with sequence similarity 107 member A.
      
 0.683
FOXJ1
Forkhead box J1.
   
 
 0.670
ABCA3
ATP binding cassette subfamily A member 3.
   
  
 0.657
SFTPB
Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
      
 0.653
VIM
Vimentin; Belongs to the intermediate filament family.
      
 0.623
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (26%) [HD]