Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDYNProdynorphin. (250 aa)    
Predicted Functional Partners:
PNOC
Prepronociceptin.
  
 
 0.975
OPRM1
Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family.
   
 0.961
OPRD1
Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.
   
 0.949
OPRK1
Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family.
   
 0.941
POMC
NPP domain-containing protein.
     
 0.939
PENK
Uncharacterized protein.
    
0.903
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A.
   
 
 0.899
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
   
 
 0.898
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
   
 
 0.871
GRIN2D
Glutamate ionotropic receptor NMDA type subunit 2D.
   
 
 0.867
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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