Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMFR | HMGCR | ENSOCUP00000043547 | ENSOCUP00000014975 | Autocrine motility factor receptor. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | 0.796 |
| AMFR | INSIG2 | ENSOCUP00000043547 | ENSOCUP00000004552 | Autocrine motility factor receptor. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.722 |
| CHAF1B | INSIG2 | ENSOCUP00000012044 | ENSOCUP00000004552 | Chromatin assembly factor 1 subunit B. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.786 |
| CYP51A1 | HMGCR | ENSOCUP00000003924 | ENSOCUP00000014975 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | 0.964 |
| CYP51A1 | HMGCS1 | ENSOCUP00000003924 | ENSOCUP00000003090 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.979 |
| CYP51A1 | INSIG2 | ENSOCUP00000003924 | ENSOCUP00000004552 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.650 |
| CYP51A1 | SREBF2 | ENSOCUP00000003924 | ENSOCUP00000020538 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. | Sterol regulatory element binding transcription factor 2. | 0.793 |
| HMGCR | AMFR | ENSOCUP00000014975 | ENSOCUP00000043547 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | Autocrine motility factor receptor. | 0.796 |
| HMGCR | CYP51A1 | ENSOCUP00000014975 | ENSOCUP00000003924 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.964 |
| HMGCR | HMGCS1 | ENSOCUP00000014975 | ENSOCUP00000003090 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.997 |
| HMGCR | INSIG2 | ENSOCUP00000014975 | ENSOCUP00000004552 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.951 |
| HMGCR | NPC1 | ENSOCUP00000014975 | ENSOCUP00000026876 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | SSD domain-containing protein. | 0.770 |
| HMGCR | NPC1L1 | ENSOCUP00000014975 | ENSOCUP00000020366 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | Niemann-Pick C1-like 1 protein. | 0.832 |
| HMGCR | SCAP | ENSOCUP00000014975 | ENSOCUP00000002746 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | SREBF chaperone. | 0.592 |
| HMGCR | SREBF2 | ENSOCUP00000014975 | ENSOCUP00000020538 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | Sterol regulatory element binding transcription factor 2. | 0.975 |
| HMGCS1 | CYP51A1 | ENSOCUP00000003090 | ENSOCUP00000003924 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.979 |
| HMGCS1 | HMGCR | ENSOCUP00000003090 | ENSOCUP00000014975 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | 0.997 |
| HMGCS1 | INSIG2 | ENSOCUP00000003090 | ENSOCUP00000004552 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.660 |
| HMGCS1 | NPC1L1 | ENSOCUP00000003090 | ENSOCUP00000020366 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Niemann-Pick C1-like 1 protein. | 0.423 |
| HMGCS1 | SREBF2 | ENSOCUP00000003090 | ENSOCUP00000020538 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Sterol regulatory element binding transcription factor 2. | 0.866 |
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