STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)    
Predicted Functional Partners:
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.998
ATG16L1
Autophagy related 16 like 1.
    
 0.995
TLR2
TIR domain-containing protein; Belongs to the Toll-like receptor family.
   
  
 0.901
NOD2
Nucleotide oligomerization domain 2 protein.
   
0.860
CASP1
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.838
LOC100358658
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.826
MYD88
Uncharacterized protein.
   
 
 0.797
TLR4
TIR domain-containing protein; Belongs to the Toll-like receptor family.
   
  
 0.793
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.744
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
   
 0.725
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (50%) [HD]