TTC5 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

TTC5

Tetratricopeptide repeat domain 5. (477 aa)

Predicted Functional Partners:

EP300

0.920

AK9

0.878

ATM

0.875

JMY

0.849

TTC4

0.816

WHAMM

0.812

ASMTL

0.801

CHEK2

0.798

TCP11L1

0.775

CAMK2D

0.773

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	ASMTL	ENSOCUP00000005312	ENSOCUP00000018505	Uncharacterized protein.	Uncharacterized protein.	0.861
AK9	TTC5	ENSOCUP00000005312	ENSOCUP00000004632	Uncharacterized protein.	Tetratricopeptide repeat domain 5.	0.878
ASMTL	AK9	ENSOCUP00000018505	ENSOCUP00000005312	Uncharacterized protein.	Uncharacterized protein.	0.861
ASMTL	TTC5	ENSOCUP00000018505	ENSOCUP00000004632	Uncharacterized protein.	Tetratricopeptide repeat domain 5.	0.801
ATM	CHEK2	ENSOCUP00000012638	ENSOCUP00000015499	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Checkpoint kinase 2.	0.998
ATM	EP300	ENSOCUP00000012638	ENSOCUP00000009840	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	E1A binding protein p300.	0.456
ATM	TTC5	ENSOCUP00000012638	ENSOCUP00000004632	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Tetratricopeptide repeat domain 5.	0.875
CAMK2D	EP300	ENSOCUP00000032333	ENSOCUP00000009840	Calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...]	E1A binding protein p300.	0.851
CAMK2D	TTC5	ENSOCUP00000032333	ENSOCUP00000004632	Calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...]	Tetratricopeptide repeat domain 5.	0.773
CHEK2	ATM	ENSOCUP00000015499	ENSOCUP00000012638	Checkpoint kinase 2.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.998
CHEK2	TTC5	ENSOCUP00000015499	ENSOCUP00000004632	Checkpoint kinase 2.	Tetratricopeptide repeat domain 5.	0.798
EP300	ATM	ENSOCUP00000009840	ENSOCUP00000012638	E1A binding protein p300.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.456
EP300	CAMK2D	ENSOCUP00000009840	ENSOCUP00000032333	E1A binding protein p300.	Calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...]	0.851
EP300	TTC5	ENSOCUP00000009840	ENSOCUP00000004632	E1A binding protein p300.	Tetratricopeptide repeat domain 5.	0.920
EP300	WHAMM	ENSOCUP00000009840	ENSOCUP00000025207	E1A binding protein p300.	WASP homolog associated with actin, golgi membranes and microtubules.	0.619
JMY	TTC5	ENSOCUP00000024628	ENSOCUP00000004632	Junction mediating and regulatory protein, p53 cofactor.	Tetratricopeptide repeat domain 5.	0.849
TCP11L1	TTC5	ENSOCUP00000013236	ENSOCUP00000004632	T-complex 11 like 1.	Tetratricopeptide repeat domain 5.	0.775
TTC4	TTC5	ENSOCUP00000021639	ENSOCUP00000004632	Tetratricopeptide repeat domain 4.	Tetratricopeptide repeat domain 5.	0.816
TTC5	AK9	ENSOCUP00000004632	ENSOCUP00000005312	Tetratricopeptide repeat domain 5.	Uncharacterized protein.	0.878
TTC5	ASMTL	ENSOCUP00000004632	ENSOCUP00000018505	Tetratricopeptide repeat domain 5.	Uncharacterized protein.	0.801