GFM2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GFM2

Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (779 aa)

Predicted Functional Partners:

MRPL27

0.948

MRRF

0.933

MRPL19

0.892

MRPL36

0.887

MRPL20

0.877

ENSOCUP00000043514

0.877

MRPL33

0.861

MRPL58

0.850

MRPL53

0.848

MRPL17

0.844

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000043514	GFM2	ENSOCUP00000043514	ENSOCUP00000004641	Uncharacterized protein.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.877
ENSOCUP00000043514	MRPL17	ENSOCUP00000043514	ENSOCUP00000004959	Uncharacterized protein.	Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.	0.979
ENSOCUP00000043514	MRPL19	ENSOCUP00000043514	ENSOCUP00000001468	Uncharacterized protein.	Mitochondrial ribosomal protein L19.	0.981
ENSOCUP00000043514	MRPL27	ENSOCUP00000043514	ENSOCUP00000003967	Uncharacterized protein.	Mitochondrial ribosomal protein L27.	0.980
ENSOCUP00000043514	MRPL33	ENSOCUP00000043514	ENSOCUP00000045989	Uncharacterized protein.	Mitochondrial ribosomal protein L33.	0.972
ENSOCUP00000043514	MRPL36	ENSOCUP00000043514	ENSOCUP00000020265	Uncharacterized protein.	Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family.	0.978
ENSOCUP00000043514	MRPL53	ENSOCUP00000043514	ENSOCUP00000013178	Uncharacterized protein.	Uncharacterized protein.	0.614
ENSOCUP00000043514	MRPL58	ENSOCUP00000043514	ENSOCUP00000000695	Uncharacterized protein.	RF_PROK_I domain-containing protein.	0.916
ENSOCUP00000043514	MRRF	ENSOCUP00000043514	ENSOCUP00000007371	Uncharacterized protein.	Mitochondrial ribosome recycling factor.	0.946
GFM2	ENSOCUP00000043514	ENSOCUP00000004641	ENSOCUP00000043514	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Uncharacterized protein.	0.877
GFM2	MRPL17	ENSOCUP00000004641	ENSOCUP00000004959	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.	0.844
GFM2	MRPL19	ENSOCUP00000004641	ENSOCUP00000001468	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Mitochondrial ribosomal protein L19.	0.892
GFM2	MRPL20	ENSOCUP00000004641	ENSOCUP00000030980	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Uncharacterized protein; Belongs to the bacterial ribosomal protein bL20 family.	0.877
GFM2	MRPL27	ENSOCUP00000004641	ENSOCUP00000003967	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Mitochondrial ribosomal protein L27.	0.948
GFM2	MRPL33	ENSOCUP00000004641	ENSOCUP00000045989	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Mitochondrial ribosomal protein L33.	0.861
GFM2	MRPL36	ENSOCUP00000004641	ENSOCUP00000020265	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family.	0.887
GFM2	MRPL53	ENSOCUP00000004641	ENSOCUP00000013178	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Uncharacterized protein.	0.848
GFM2	MRPL58	ENSOCUP00000004641	ENSOCUP00000000695	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	RF_PROK_I domain-containing protein.	0.850
GFM2	MRRF	ENSOCUP00000004641	ENSOCUP00000007371	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Mitochondrial ribosome recycling factor.	0.933
MRPL17	ENSOCUP00000043514	ENSOCUP00000004959	ENSOCUP00000043514	Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.	Uncharacterized protein.	0.979

page 1 of 6

Server load: low (40%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Fusion

© STRING Consortium 2025

Credits

Access

Info

About