RHOJ protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGDIB	ITSN2	ENSOCUP00000005200	ENSOCUP00000019448	Rho GDP dissociation inhibitor beta.	Intersectin 2.	0.476
ARHGDIB	RHOJ	ENSOCUP00000005200	ENSOCUP00000004645	Rho GDP dissociation inhibitor beta.	Ras homolog family member J.	0.778
ARHGDIB	RHOQ	ENSOCUP00000005200	ENSOCUP00000034793	Rho GDP dissociation inhibitor beta.	Uncharacterized protein.	0.778
DOCK8	RHOJ	ENSOCUP00000002796	ENSOCUP00000004645	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Ras homolog family member J.	0.840
DOCK8	RHOQ	ENSOCUP00000002796	ENSOCUP00000034793	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Uncharacterized protein.	0.791
ITSN1	ITSN2	ENSOCUP00000047769	ENSOCUP00000019448	Intersectin 1.	Intersectin 2.	0.829
ITSN1	PAK6	ENSOCUP00000047769	ENSOCUP00000023590	Intersectin 1.	Non-specific serine/threonine protein kinase.	0.436
ITSN1	RHOJ	ENSOCUP00000047769	ENSOCUP00000004645	Intersectin 1.	Ras homolog family member J.	0.769
ITSN1	RHOQ	ENSOCUP00000047769	ENSOCUP00000034793	Intersectin 1.	Uncharacterized protein.	0.805
ITSN2	ARHGDIB	ENSOCUP00000019448	ENSOCUP00000005200	Intersectin 2.	Rho GDP dissociation inhibitor beta.	0.476
ITSN2	ITSN1	ENSOCUP00000019448	ENSOCUP00000047769	Intersectin 2.	Intersectin 1.	0.829
ITSN2	PAK1	ENSOCUP00000019448	ENSOCUP00000036636	Intersectin 2.	Non-specific serine/threonine protein kinase.	0.548
ITSN2	PAK2	ENSOCUP00000019448	ENSOCUP00000007111	Intersectin 2.	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	0.495
ITSN2	PAK6	ENSOCUP00000019448	ENSOCUP00000023590	Intersectin 2.	Non-specific serine/threonine protein kinase.	0.471
ITSN2	RHOJ	ENSOCUP00000019448	ENSOCUP00000004645	Intersectin 2.	Ras homolog family member J.	0.835
ITSN2	RHOQ	ENSOCUP00000019448	ENSOCUP00000034793	Intersectin 2.	Uncharacterized protein.	0.835
LOC100340957	RHOJ	ENSOCUP00000017559	ENSOCUP00000004645	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Ras homolog family member J.	0.762
LOC100340957	RHOQ	ENSOCUP00000017559	ENSOCUP00000034793	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	Uncharacterized protein.	0.935
PAK1	ITSN2	ENSOCUP00000036636	ENSOCUP00000019448	Non-specific serine/threonine protein kinase.	Intersectin 2.	0.548
PAK1	PAK2	ENSOCUP00000036636	ENSOCUP00000007111	Non-specific serine/threonine protein kinase.	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	0.997