Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASC4Cancer susceptibility 4. (437 aa)    
Predicted Functional Partners:
SMIM7
Small integral membrane protein 7.
      
 0.851
CCDC186
Coiled-coil domain containing 186.
      
 0.799
TM9SF3
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
   
  
 0.792
TMEM87A
Transmembrane protein 87A.
   
  
 0.709
TBC1D25
TBC1 domain family member 25.
    
 
 0.672
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
     
 0.661
VTI1B
Vesicle transport through interaction with t-SNAREs 1B.
     
 0.653
ARFIP2
ADP ribosylation factor interacting protein 2.
   
  
 0.609
DNTTIP2
Deoxynucleotidyltransferase terminal interacting protein 2.
      
 0.591
GRAMD2B
GRAM domain containing 2B.
    
   0.567
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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