TMPRSS11B protein (Oryctolagus cuniculus) - STRING interaction network

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Score

TMPRSS11B

Transmembrane serine protease 11B. (404 aa)

Predicted Functional Partners:

G1TH80_RABIT

0.540

MST1R

0.539

MET

0.537

G1TX71_RABIT

0.517

CMA1

0.515

LOC100340108

0.508

KRT5

0.472

LOC100346323

0.470

CTSG

0.449

TMPRSS4

0.434

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMA1	LOC100340108	ENSOCUP00000020875	ENSOCUP00000035493	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.524
CMA1	LOC100346323	ENSOCUP00000020875	ENSOCUP00000015500	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Uncharacterized protein.	0.470
CMA1	MET	ENSOCUP00000020875	ENSOCUP00000003111	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.537
CMA1	MST1R	ENSOCUP00000020875	ENSOCUP00000008078	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Macrophage stimulating 1 receptor.	0.570
CMA1	TMPRSS11B	ENSOCUP00000020875	ENSOCUP00000004700	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Transmembrane serine protease 11B.	0.515
CTSG	LOC100340108	ENSOCUP00000001158	ENSOCUP00000035493	Cathepsin G.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.493
CTSG	LOC100346323	ENSOCUP00000001158	ENSOCUP00000015500	Cathepsin G.	Uncharacterized protein.	0.470
CTSG	MET	ENSOCUP00000001158	ENSOCUP00000003111	Cathepsin G.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.537
CTSG	MST1R	ENSOCUP00000001158	ENSOCUP00000008078	Cathepsin G.	Macrophage stimulating 1 receptor.	0.539
CTSG	TMPRSS11B	ENSOCUP00000001158	ENSOCUP00000004700	Cathepsin G.	Transmembrane serine protease 11B.	0.449
CTSG	TMPRSS4	ENSOCUP00000001158	ENSOCUP00000014592	Cathepsin G.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.480
G1TH80_RABIT	LOC100340108	ENSOCUP00000016285	ENSOCUP00000035493	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.557
G1TH80_RABIT	LOC100346323	ENSOCUP00000016285	ENSOCUP00000015500	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.470
G1TH80_RABIT	MET	ENSOCUP00000016285	ENSOCUP00000003111	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.537
G1TH80_RABIT	MST1R	ENSOCUP00000016285	ENSOCUP00000008078	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.539
G1TH80_RABIT	TMPRSS11B	ENSOCUP00000016285	ENSOCUP00000004700	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Transmembrane serine protease 11B.	0.540
G1TX71_RABIT	LOC100340108	ENSOCUP00000021671	ENSOCUP00000035493	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.523
G1TX71_RABIT	LOC100346323	ENSOCUP00000021671	ENSOCUP00000015500	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.470
G1TX71_RABIT	MET	ENSOCUP00000021671	ENSOCUP00000003111	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.537
G1TX71_RABIT	MST1R	ENSOCUP00000021671	ENSOCUP00000008078	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.539