Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMDHD1Amidohydrolase domain containing 1. (491 aa)    
Predicted Functional Partners:
UROC1
Urocanate hydratase 1.
  
 
 0.986
FTCD
FTCD_C domain-containing protein.
   
 
 0.979
HAL
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
 
 0.901
UPRT
Uracil phosphoribosyltransferase homolog.
  
 
 0.741
ZXDB
Uncharacterized protein.
   
 
 0.736
ZXDC
ZXD family zinc finger C.
   
 
 0.736
AGMAT
Agmatinase; Belongs to the arginase family.
  
 
 0.709
ADSL
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.579
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.572
AGXT
Serine--pyruvate aminotransferase.
  
  
 0.565
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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