LOC100351599 protein (Oryctolagus cuniculus)

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LOC100351599

Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)

Predicted Functional Partners:

ENSOCUP00000032843

0.559

AASDH

0.526

WRN

0.507

CYP7B1

0.502

FDX1

0.477

NBN

0.445

CYP7A1

0.417

BARD1

0.416

NDUFAB1

0.415

PALB2

0.415

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AASDH	CYP7A1	ENSOCUP00000010497	ENSOCUP00000010572	Aminoadipate-semialdehyde dehydrogenase.	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	0.563
AASDH	CYP7B1	ENSOCUP00000010497	ENSOCUP00000032097	Aminoadipate-semialdehyde dehydrogenase.	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.	0.528
AASDH	ENSOCUP00000032843	ENSOCUP00000010497	ENSOCUP00000032843	Aminoadipate-semialdehyde dehydrogenase.	Uncharacterized protein.	0.580
AASDH	FDX1	ENSOCUP00000010497	ENSOCUP00000046511	Aminoadipate-semialdehyde dehydrogenase.	2Fe-2S ferredoxin-type domain-containing protein.	0.559
AASDH	LOC100351599	ENSOCUP00000010497	ENSOCUP00000004923	Aminoadipate-semialdehyde dehydrogenase.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.526
AASDH	NDUFAB1	ENSOCUP00000010497	ENSOCUP00000007307	Aminoadipate-semialdehyde dehydrogenase.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.990
AASDH	PALB2	ENSOCUP00000010497	ENSOCUP00000007310	Aminoadipate-semialdehyde dehydrogenase.	Partner and localizer of BRCA2.	0.991
BARD1	LOC100351599	ENSOCUP00000001334	ENSOCUP00000004923	BRCA1 associated RING domain 1.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.416
BARD1	NBN	ENSOCUP00000001334	ENSOCUP00000029655	BRCA1 associated RING domain 1.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.991
BARD1	NDUFAB1	ENSOCUP00000001334	ENSOCUP00000007307	BRCA1 associated RING domain 1.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.896
BARD1	PALB2	ENSOCUP00000001334	ENSOCUP00000007310	BRCA1 associated RING domain 1.	Partner and localizer of BRCA2.	0.991
BARD1	WRN	ENSOCUP00000001334	ENSOCUP00000010872	BRCA1 associated RING domain 1.	WRN RecQ like helicase.	0.987
CYP7A1	AASDH	ENSOCUP00000010572	ENSOCUP00000010497	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	Aminoadipate-semialdehyde dehydrogenase.	0.563
CYP7A1	ENSOCUP00000032843	ENSOCUP00000010572	ENSOCUP00000032843	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	Uncharacterized protein.	0.495
CYP7A1	FDX1	ENSOCUP00000010572	ENSOCUP00000046511	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	2Fe-2S ferredoxin-type domain-containing protein.	0.477
CYP7A1	LOC100351599	ENSOCUP00000010572	ENSOCUP00000004923	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.417
CYP7A1	NDUFAB1	ENSOCUP00000010572	ENSOCUP00000007307	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.415
CYP7A1	PALB2	ENSOCUP00000010572	ENSOCUP00000007310	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	Partner and localizer of BRCA2.	0.415
CYP7B1	AASDH	ENSOCUP00000032097	ENSOCUP00000010497	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.	Aminoadipate-semialdehyde dehydrogenase.	0.528
CYP7B1	ENSOCUP00000032843	ENSOCUP00000032097	ENSOCUP00000032843	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.546