STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIGKGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (358 aa)    
Predicted Functional Partners:
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
    
 0.995
PIGT
Uncharacterized protein.
   
 0.994
PIGS
Phosphatidylinositol glycan anchor biosynthesis class S.
   
 0.970
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
    
 0.967
ENSOCUP00000045854
Uncharacterized protein.
   
 0.927
PIGB
Mannosyltransferase.
      
 0.903
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
    
 
 0.862
PIGZ
Mannosyltransferase.
      
 0.812
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
      
 0.801
PGAP3
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
    
 
 0.789
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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