STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCN1GCN1 activator of EIF2AK4. (2633 aa)    
Predicted Functional Partners:
ABCF3
ATP binding cassette subfamily F member 3.
   
 
 0.997
RPS15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
   
 
 0.888
EIF2S1
Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction catalyzed [...]
   
 
 0.885
EIF2AK4
Eukaryotic translation initiation factor 2 alpha kinase 4.
   
 
 0.880
G1TYL6_RABIT
Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
 
 
   0.875
G1TJR3_RABIT
Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
 
 
   0.874
LOC100353302
Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
 
 
   0.864
G1TI85_RABIT
Ribosomal_L19e domain-containing protein.
 
 
   0.863
RPS5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.861
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
 
 0.841
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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