Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RRM2Ribonucleotide reductase regulatory subunit M2. (367 aa)    
Predicted Functional Partners:
RRM1
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.999
RRM2B
Ribonucleotide reductase regulatory TP53 inducible subunit M2B.
   
 0.989
ZWINT
ZW10 interacting kinetochore protein.
   
  
 0.937
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.921
DTYMK
Deoxythymidylate kinase.
   
 
 0.917
CCNF
Cyclin F; Belongs to the cyclin family.
   
 
 0.905
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.901
TYMS
Thymidylate synthetase.
   
  
 0.901
CEP55
Centrosomal protein 55.
   
  
 0.901
MCM4
DNA helicase; Belongs to the MCM family.
   
 
 0.895
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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