KDM2B protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KDM2B

Lysine demethylase 2B. (1341 aa)

Predicted Functional Partners:

PCGF1

0.996

SKP1

0.988

RYBP

0.986

RNF2

0.980

NEDD8

0.968

YAF2

0.959

ENSOCUP00000031260

0.953

ENSOCUP00000046782

0.953

ENSOCUP00000048996

0.953

ENSOCUP00000038972

0.952

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000031260	KDM2B	ENSOCUP00000031260	ENSOCUP00000005165	Uncharacterized protein; Belongs to the SKP1 family.	Lysine demethylase 2B.	0.953
ENSOCUP00000031260	NEDD8	ENSOCUP00000031260	ENSOCUP00000002526	Uncharacterized protein; Belongs to the SKP1 family.	NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity).	0.787
ENSOCUP00000031260	PCGF1	ENSOCUP00000031260	ENSOCUP00000034574	Uncharacterized protein; Belongs to the SKP1 family.	Polycomb group ring finger 1.	0.746
ENSOCUP00000038972	KDM2B	ENSOCUP00000038972	ENSOCUP00000005165	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	Lysine demethylase 2B.	0.952
ENSOCUP00000038972	NEDD8	ENSOCUP00000038972	ENSOCUP00000002526	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity).	0.783
ENSOCUP00000038972	PCGF1	ENSOCUP00000038972	ENSOCUP00000034574	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	Polycomb group ring finger 1.	0.698
ENSOCUP00000046782	KDM2B	ENSOCUP00000046782	ENSOCUP00000005165	Skp1_POZ domain-containing protein.	Lysine demethylase 2B.	0.953
ENSOCUP00000046782	NEDD8	ENSOCUP00000046782	ENSOCUP00000002526	Skp1_POZ domain-containing protein.	NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity).	0.787
ENSOCUP00000046782	PCGF1	ENSOCUP00000046782	ENSOCUP00000034574	Skp1_POZ domain-containing protein.	Polycomb group ring finger 1.	0.746
ENSOCUP00000048996	KDM2B	ENSOCUP00000048996	ENSOCUP00000005165	Uncharacterized protein; Belongs to the SKP1 family.	Lysine demethylase 2B.	0.953
ENSOCUP00000048996	NEDD8	ENSOCUP00000048996	ENSOCUP00000002526	Uncharacterized protein; Belongs to the SKP1 family.	NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity).	0.787
ENSOCUP00000048996	PCGF1	ENSOCUP00000048996	ENSOCUP00000034574	Uncharacterized protein; Belongs to the SKP1 family.	Polycomb group ring finger 1.	0.746
KDM2B	ENSOCUP00000031260	ENSOCUP00000005165	ENSOCUP00000031260	Lysine demethylase 2B.	Uncharacterized protein; Belongs to the SKP1 family.	0.953
KDM2B	ENSOCUP00000038972	ENSOCUP00000005165	ENSOCUP00000038972	Lysine demethylase 2B.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.952
KDM2B	ENSOCUP00000046782	ENSOCUP00000005165	ENSOCUP00000046782	Lysine demethylase 2B.	Skp1_POZ domain-containing protein.	0.953
KDM2B	ENSOCUP00000048996	ENSOCUP00000005165	ENSOCUP00000048996	Lysine demethylase 2B.	Uncharacterized protein; Belongs to the SKP1 family.	0.953
KDM2B	NEDD8	ENSOCUP00000005165	ENSOCUP00000002526	Lysine demethylase 2B.	NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity).	0.968
KDM2B	PCGF1	ENSOCUP00000005165	ENSOCUP00000034574	Lysine demethylase 2B.	Polycomb group ring finger 1.	0.996
KDM2B	RNF2	ENSOCUP00000005165	ENSOCUP00000004231	Lysine demethylase 2B.	RING-type domain-containing protein.	0.980
KDM2B	RYBP	ENSOCUP00000005165	ENSOCUP00000010083	Lysine demethylase 2B.	RING1 and YY1 binding protein.	0.986