Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LINGO1Leucine rich repeat and Ig domain containing 1. (693 aa)    
Predicted Functional Partners:
NGFR
Nerve growth factor receptor.
    
 0.970
OMG
Oligodendrocyte myelin glycoprotein.
   
0.939
RTN4
Reticulon.
   
 0.912
MAG
Uncharacterized protein.
   
 0.869
RTN3
Reticulon.
   
 0.811
RTN2
Reticulon.
   
 0.803
LINGO2
Leucine rich repeat and Ig domain containing 2.
   
   0.768
RHOA
Ras homolog family member A.
    
 0.752
SLC17A7
Solute carrier family 17 member 7.
   
  
 0.622
MBP
Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity); Belongs to the myelin basic protein family.
    
 
 0.604
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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