ALPK3 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ALPK3

Alpha kinase 3. (1548 aa)

Predicted Functional Partners:

ATP8B2

0.693

BOD1L1

0.610

CCDC174

0.593

MRPL42

0.590

EIF2AK3

0.558

INTS5

0.554

IER3IP1

0.509

PYGO2

0.447

ELK1

0.432

TIMM17A

0.429

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPK3	ATP8B2	ENSOCUP00000005190	ENSOCUP00000042487	Alpha kinase 3.	PhoLip_ATPase_N domain-containing protein.	0.693
ALPK3	BOD1L1	ENSOCUP00000005190	ENSOCUP00000007824	Alpha kinase 3.	Biorientation of chromosomes in cell division 1 like 1.	0.610
ALPK3	CCDC174	ENSOCUP00000005190	ENSOCUP00000007302	Alpha kinase 3.	Coiled-coil domain containing 174.	0.593
ALPK3	EIF2AK3	ENSOCUP00000005190	ENSOCUP00000010720	Alpha kinase 3.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.558
ALPK3	ELK1	ENSOCUP00000005190	ENSOCUP00000042083	Alpha kinase 3.	ETS transcription factor ELK1.	0.432
ALPK3	IER3IP1	ENSOCUP00000005190	ENSOCUP00000010806	Alpha kinase 3.	Uncharacterized protein.	0.509
ALPK3	INTS5	ENSOCUP00000005190	ENSOCUP00000014840	Alpha kinase 3.	Integrator complex subunit 5.	0.554
ALPK3	MRPL42	ENSOCUP00000005190	ENSOCUP00000009404	Alpha kinase 3.	Mitochondrial ribosomal protein L42.	0.590
ALPK3	PYGO2	ENSOCUP00000005190	ENSOCUP00000029772	Alpha kinase 3.	Pygopus family PHD finger 2.	0.447
ALPK3	TIMM17A	ENSOCUP00000005190	ENSOCUP00000006485	Alpha kinase 3.	Uncharacterized protein.	0.429
ATP8B2	ALPK3	ENSOCUP00000042487	ENSOCUP00000005190	PhoLip_ATPase_N domain-containing protein.	Alpha kinase 3.	0.693
ATP8B2	BOD1L1	ENSOCUP00000042487	ENSOCUP00000007824	PhoLip_ATPase_N domain-containing protein.	Biorientation of chromosomes in cell division 1 like 1.	0.564
BOD1L1	ALPK3	ENSOCUP00000007824	ENSOCUP00000005190	Biorientation of chromosomes in cell division 1 like 1.	Alpha kinase 3.	0.610
BOD1L1	ATP8B2	ENSOCUP00000007824	ENSOCUP00000042487	Biorientation of chromosomes in cell division 1 like 1.	PhoLip_ATPase_N domain-containing protein.	0.564
CCDC174	ALPK3	ENSOCUP00000007302	ENSOCUP00000005190	Coiled-coil domain containing 174.	Alpha kinase 3.	0.593
EIF2AK3	ALPK3	ENSOCUP00000010720	ENSOCUP00000005190	Eukaryotic translation initiation factor 2 alpha kinase 3.	Alpha kinase 3.	0.558
EIF2AK3	IER3IP1	ENSOCUP00000010720	ENSOCUP00000010806	Eukaryotic translation initiation factor 2 alpha kinase 3.	Uncharacterized protein.	0.404
ELK1	ALPK3	ENSOCUP00000042083	ENSOCUP00000005190	ETS transcription factor ELK1.	Alpha kinase 3.	0.432
IER3IP1	ALPK3	ENSOCUP00000010806	ENSOCUP00000005190	Uncharacterized protein.	Alpha kinase 3.	0.509
IER3IP1	EIF2AK3	ENSOCUP00000010806	ENSOCUP00000010720	Uncharacterized protein.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.404