PPP6R3 protein (Oryctolagus cuniculus) - STRING interaction network

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PPP6R3

Protein phosphatase 6 regulatory subunit 3. (930 aa)

Predicted Functional Partners:

PPP6C

0.960

ANKRD28

0.880

SF3B1

0.656

PPP2CA

0.639

SAP30BP

0.635

ANKRD52

0.619

ANKRD44

0.615

ANKRD66

0.607

PPP4C

0.604

ZNF326

0.580

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD28	PPP4C	ENSOCUP00000007413	ENSOCUP00000005480	Ankyrin repeat domain 28.	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	0.570
ANKRD28	PPP6C	ENSOCUP00000007413	ENSOCUP00000008086	Ankyrin repeat domain 28.	Serine/threonine-protein phosphatase.	0.869
ANKRD28	PPP6R3	ENSOCUP00000007413	ENSOCUP00000005260	Ankyrin repeat domain 28.	Protein phosphatase 6 regulatory subunit 3.	0.880
ANKRD44	PPP4C	ENSOCUP00000016984	ENSOCUP00000005480	Ankyrin repeat domain 44.	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	0.613
ANKRD44	PPP6C	ENSOCUP00000016984	ENSOCUP00000008086	Ankyrin repeat domain 44.	Serine/threonine-protein phosphatase.	0.724
ANKRD44	PPP6R3	ENSOCUP00000016984	ENSOCUP00000005260	Ankyrin repeat domain 44.	Protein phosphatase 6 regulatory subunit 3.	0.615
ANKRD52	PPP4C	ENSOCUP00000026861	ENSOCUP00000005480	Ankyrin repeat domain 52.	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	0.515
ANKRD52	PPP6C	ENSOCUP00000026861	ENSOCUP00000008086	Ankyrin repeat domain 52.	Serine/threonine-protein phosphatase.	0.767
ANKRD52	PPP6R3	ENSOCUP00000026861	ENSOCUP00000005260	Ankyrin repeat domain 52.	Protein phosphatase 6 regulatory subunit 3.	0.619
ANKRD66	PPP6C	ENSOCUP00000026719	ENSOCUP00000008086	Ankyrin repeat domain 66.	Serine/threonine-protein phosphatase.	0.689
ANKRD66	PPP6R3	ENSOCUP00000026719	ENSOCUP00000005260	Ankyrin repeat domain 66.	Protein phosphatase 6 regulatory subunit 3.	0.607
PPP2CA	PPP4C	ENSOCUP00000013713	ENSOCUP00000005480	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity).	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	0.566
PPP2CA	PPP6R3	ENSOCUP00000013713	ENSOCUP00000005260	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity).	Protein phosphatase 6 regulatory subunit 3.	0.639
PPP4C	ANKRD28	ENSOCUP00000005480	ENSOCUP00000007413	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Ankyrin repeat domain 28.	0.570
PPP4C	ANKRD44	ENSOCUP00000005480	ENSOCUP00000016984	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Ankyrin repeat domain 44.	0.613
PPP4C	ANKRD52	ENSOCUP00000005480	ENSOCUP00000026861	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Ankyrin repeat domain 52.	0.515
PPP4C	PPP2CA	ENSOCUP00000005480	ENSOCUP00000013713	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity).	0.566
PPP4C	PPP6R3	ENSOCUP00000005480	ENSOCUP00000005260	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Protein phosphatase 6 regulatory subunit 3.	0.604
PPP6C	ANKRD28	ENSOCUP00000008086	ENSOCUP00000007413	Serine/threonine-protein phosphatase.	Ankyrin repeat domain 28.	0.869
PPP6C	ANKRD44	ENSOCUP00000008086	ENSOCUP00000016984	Serine/threonine-protein phosphatase.	Ankyrin repeat domain 44.	0.724