TIMP2 protein (Oryctolagus cuniculus) - STRING interaction network

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TIMP2

Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family. (1218 aa)

Predicted Functional Partners:

DHX33

0.947

DGCR8

0.799

USP25

0.746

USP28

0.717

USP5

0.712

MYC

0.702

NOP58

0.699

NPM1-2

0.690

FBL

0.678

USP30

0.675

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGCR8	TIMP2	ENSOCUP00000003136	ENSOCUP00000005290	DGCR8 microprocessor complex subunit.	Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.	0.799
DHX33	FBL	ENSOCUP00000024866	ENSOCUP00000007791	DEAH-box helicase 33.	Fibrillarin.	0.468
DHX33	NOP58	ENSOCUP00000024866	ENSOCUP00000031460	DEAH-box helicase 33.	NOP58 ribonucleoprotein.	0.469
DHX33	TIMP2	ENSOCUP00000024866	ENSOCUP00000005290	DEAH-box helicase 33.	Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.	0.947
FBL	DHX33	ENSOCUP00000007791	ENSOCUP00000024866	Fibrillarin.	DEAH-box helicase 33.	0.468
FBL	MYC	ENSOCUP00000007791	ENSOCUP00000012281	Fibrillarin.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.570
FBL	NOP58	ENSOCUP00000007791	ENSOCUP00000031460	Fibrillarin.	NOP58 ribonucleoprotein.	0.999
FBL	NPM1-2	ENSOCUP00000007791	ENSOCUP00000009569	Fibrillarin.	Uncharacterized protein.	0.839
FBL	TIMP2	ENSOCUP00000007791	ENSOCUP00000005290	Fibrillarin.	Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.	0.678
MYC	FBL	ENSOCUP00000012281	ENSOCUP00000007791	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	Fibrillarin.	0.570
MYC	NPM1-2	ENSOCUP00000012281	ENSOCUP00000009569	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	Uncharacterized protein.	0.615
MYC	TIMP2	ENSOCUP00000012281	ENSOCUP00000005290	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.	0.702
MYC	USP25	ENSOCUP00000012281	ENSOCUP00000004100	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.	0.777
MYC	USP28	ENSOCUP00000012281	ENSOCUP00000027870	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.	0.976
NOP58	DHX33	ENSOCUP00000031460	ENSOCUP00000024866	NOP58 ribonucleoprotein.	DEAH-box helicase 33.	0.469
NOP58	FBL	ENSOCUP00000031460	ENSOCUP00000007791	NOP58 ribonucleoprotein.	Fibrillarin.	0.999
NOP58	NPM1-2	ENSOCUP00000031460	ENSOCUP00000009569	NOP58 ribonucleoprotein.	Uncharacterized protein.	0.745
NOP58	TIMP2	ENSOCUP00000031460	ENSOCUP00000005290	NOP58 ribonucleoprotein.	Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.	0.699
NPM1-2	FBL	ENSOCUP00000009569	ENSOCUP00000007791	Uncharacterized protein.	Fibrillarin.	0.839
NPM1-2	MYC	ENSOCUP00000009569	ENSOCUP00000012281	Uncharacterized protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.615

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