Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2BU1Histone H2B; Belongs to the histone H2B family. (67 aa)    
Predicted Functional Partners:
LOC100357927
Histone domain-containing protein.
   
 0.841
H3C13
Histone H3; Belongs to the histone H3 family.
   
 0.841
LOC100345683
Histone H3; Belongs to the histone H3 family.
   
 0.841
H3-3A
Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]
   
 0.841
LOC100344410
Histone domain-containing protein.
   
 0.841
G1TX56_RABIT
Histone H3; Belongs to the histone H3 family.
   
 0.841
G1TJR7_RABIT
Histone H3; Belongs to the histone H3 family.
   
 0.841
ENSOCUP00000042583
Histone H3; Belongs to the histone H3 family.
   
 0.841
H3F3B
Histone H3; Belongs to the histone H3 family.
   
 0.840
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
    
 0.802
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.