Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G1SQF5_RABITAAA domain-containing protein; Belongs to the AAA ATPase family. (401 aa)    
Predicted Functional Partners:
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 
 0.853
CDC20B
Cell division cycle 20B.
   
 
 0.798
MAD2L1BP
MAD2L1 binding protein.
    
 
 0.792
MELK
Non-specific serine/threonine protein kinase.
   
 
 0.750
ARSA
Arylsulfatase A.
    
  0.737
UBXN7
UBX domain-containing protein.
   
 0.728
DMC1
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
   
 0.704
ORC1
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 
 0.698
BUB1B
Uncharacterized protein.
   
   0.693
MAD2L2
Mitotic arrest deficient 2 like 2.
    
 
 0.680
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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