EMC4 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EMC4

ER membrane protein complex subunit 4; Belongs to the EMC4 family. (183 aa)

Predicted Functional Partners:

EMC1

0.999

EMC2

0.999

EMC7

0.992

EMC3

0.989

EMC9

0.978

VPS28

0.948

MMGT1

0.945

ENSOCUP00000040641

0.931

ENSOCUP00000034905

0.926

DCTN4

0.902

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCTN4	EMC1	ENSOCUP00000049261	ENSOCUP00000000238	Dynactin subunit 4.	ER membrane protein complex subunit 1.	0.911
DCTN4	EMC2	ENSOCUP00000049261	ENSOCUP00000032373	Dynactin subunit 4.	ER membrane protein complex subunit 2.	0.901
DCTN4	EMC3	ENSOCUP00000049261	ENSOCUP00000003738	Dynactin subunit 4.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.817
DCTN4	EMC4	ENSOCUP00000049261	ENSOCUP00000005335	Dynactin subunit 4.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.902
DCTN4	ENSOCUP00000040641	ENSOCUP00000049261	ENSOCUP00000040641	Dynactin subunit 4.	Uncharacterized protein.	0.817
EMC1	DCTN4	ENSOCUP00000000238	ENSOCUP00000049261	ER membrane protein complex subunit 1.	Dynactin subunit 4.	0.911
EMC1	EMC2	ENSOCUP00000000238	ENSOCUP00000032373	ER membrane protein complex subunit 1.	ER membrane protein complex subunit 2.	0.999
EMC1	EMC3	ENSOCUP00000000238	ENSOCUP00000003738	ER membrane protein complex subunit 1.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.984
EMC1	EMC4	ENSOCUP00000000238	ENSOCUP00000005335	ER membrane protein complex subunit 1.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.999
EMC1	EMC7	ENSOCUP00000000238	ENSOCUP00000007676	ER membrane protein complex subunit 1.	ER membrane protein complex subunit 7.	0.993
EMC1	EMC9	ENSOCUP00000000238	ENSOCUP00000029334	ER membrane protein complex subunit 1.	ER membrane protein complex subunit 9.	0.979
EMC1	ENSOCUP00000034905	ENSOCUP00000000238	ENSOCUP00000034905	ER membrane protein complex subunit 1.	Uncharacterized protein.	0.927
EMC1	ENSOCUP00000040641	ENSOCUP00000000238	ENSOCUP00000040641	ER membrane protein complex subunit 1.	Uncharacterized protein.	0.903
EMC1	MMGT1	ENSOCUP00000000238	ENSOCUP00000027002	ER membrane protein complex subunit 1.	Uncharacterized protein.	0.969
EMC2	DCTN4	ENSOCUP00000032373	ENSOCUP00000049261	ER membrane protein complex subunit 2.	Dynactin subunit 4.	0.901
EMC2	EMC1	ENSOCUP00000032373	ENSOCUP00000000238	ER membrane protein complex subunit 2.	ER membrane protein complex subunit 1.	0.999
EMC2	EMC3	ENSOCUP00000032373	ENSOCUP00000003738	ER membrane protein complex subunit 2.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.987
EMC2	EMC4	ENSOCUP00000032373	ENSOCUP00000005335	ER membrane protein complex subunit 2.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.999
EMC2	EMC7	ENSOCUP00000032373	ENSOCUP00000007676	ER membrane protein complex subunit 2.	ER membrane protein complex subunit 7.	0.984
EMC2	EMC9	ENSOCUP00000032373	ENSOCUP00000029334	ER membrane protein complex subunit 2.	ER membrane protein complex subunit 9.	0.989