MDH1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

MDH1

Malate dehydrogenase. (334 aa)

Predicted Functional Partners:

MDH2

0.991

CS

0.979

ME1

0.967

GOT1

0.955

GLUD1

0.938

ACLY

0.935

GOT2

0.932

PCK2

0.928

ME2

0.919

ME3

0.911

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	CS	ENSOCUP00000029663	ENSOCUP00000049078	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Citrate synthase; Belongs to the citrate synthase family.	0.992
ACLY	GLUD1	ENSOCUP00000029663	ENSOCUP00000039862	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.912
ACLY	GOT1	ENSOCUP00000029663	ENSOCUP00000033978	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Aspartate aminotransferase.	0.915
ACLY	GOT2	ENSOCUP00000029663	ENSOCUP00000047949	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).	0.860
ACLY	MDH1	ENSOCUP00000029663	ENSOCUP00000005340	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malate dehydrogenase.	0.935
ACLY	MDH2	ENSOCUP00000029663	ENSOCUP00000035179	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malate dehydrogenase 2.	0.949
ACLY	ME1	ENSOCUP00000029663	ENSOCUP00000009305	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malic enzyme.	0.756
ACLY	ME2	ENSOCUP00000029663	ENSOCUP00000010702	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malic enzyme.	0.605
ACLY	ME3	ENSOCUP00000029663	ENSOCUP00000035588	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malic enzyme; Belongs to the malic enzymes family.	0.529
ACLY	PCK2	ENSOCUP00000029663	ENSOCUP00000002461	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Phosphoenolpyruvate carboxykinase 2, mitochondrial.	0.914
CS	ACLY	ENSOCUP00000049078	ENSOCUP00000029663	Citrate synthase; Belongs to the citrate synthase family.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.992
CS	GLUD1	ENSOCUP00000049078	ENSOCUP00000039862	Citrate synthase; Belongs to the citrate synthase family.	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.964
CS	GOT1	ENSOCUP00000049078	ENSOCUP00000033978	Citrate synthase; Belongs to the citrate synthase family.	Aspartate aminotransferase.	0.948
CS	GOT2	ENSOCUP00000049078	ENSOCUP00000047949	Citrate synthase; Belongs to the citrate synthase family.	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).	0.971
CS	MDH1	ENSOCUP00000049078	ENSOCUP00000005340	Citrate synthase; Belongs to the citrate synthase family.	Malate dehydrogenase.	0.979
CS	MDH2	ENSOCUP00000049078	ENSOCUP00000035179	Citrate synthase; Belongs to the citrate synthase family.	Malate dehydrogenase 2.	0.997
CS	ME1	ENSOCUP00000049078	ENSOCUP00000009305	Citrate synthase; Belongs to the citrate synthase family.	Malic enzyme.	0.915
CS	ME2	ENSOCUP00000049078	ENSOCUP00000010702	Citrate synthase; Belongs to the citrate synthase family.	Malic enzyme.	0.902
CS	ME3	ENSOCUP00000049078	ENSOCUP00000035588	Citrate synthase; Belongs to the citrate synthase family.	Malic enzyme; Belongs to the malic enzymes family.	0.917
CS	PCK2	ENSOCUP00000049078	ENSOCUP00000002461	Citrate synthase; Belongs to the citrate synthase family.	Phosphoenolpyruvate carboxykinase 2, mitochondrial.	0.907