NUDT2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

NUDT2

Nudix hydrolase 2. (147 aa)

Predicted Functional Partners:

ITPA

0.944

NME6

0.921

NUDT22

0.900

NUDT12

0.899

ENPP3

0.897

ENPP1

0.886

CTPS2

0.879

NUDT18

0.879

CTPS1

0.879

NME1

0.871

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTPS1	CTPS2	ENSOCUP00000014016	ENSOCUP00000002373	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.987
CTPS1	ENPP1	ENSOCUP00000014016	ENSOCUP00000049040	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Uncharacterized protein.	0.870
CTPS1	ENPP3	ENSOCUP00000014016	ENSOCUP00000012418	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleotide pyrophosphatase/phosphodiesterase 3.	0.870
CTPS1	ITPA	ENSOCUP00000014016	ENSOCUP00000003524	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.609
CTPS1	NME1	ENSOCUP00000014016	ENSOCUP00000025502	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase.	0.871
CTPS1	NME6	ENSOCUP00000014016	ENSOCUP00000000478	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase.	0.878
CTPS1	NUDT2	ENSOCUP00000014016	ENSOCUP00000005385	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nudix hydrolase 2.	0.879
CTPS2	CTPS1	ENSOCUP00000002373	ENSOCUP00000014016	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.987
CTPS2	ENPP1	ENSOCUP00000002373	ENSOCUP00000049040	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Uncharacterized protein.	0.866
CTPS2	ENPP3	ENSOCUP00000002373	ENSOCUP00000012418	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleotide pyrophosphatase/phosphodiesterase 3.	0.866
CTPS2	ITPA	ENSOCUP00000002373	ENSOCUP00000003524	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.709
CTPS2	NME1	ENSOCUP00000002373	ENSOCUP00000025502	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase.	0.871
CTPS2	NME6	ENSOCUP00000002373	ENSOCUP00000000478	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase.	0.878
CTPS2	NUDT2	ENSOCUP00000002373	ENSOCUP00000005385	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nudix hydrolase 2.	0.879
ENPP1	CTPS1	ENSOCUP00000049040	ENSOCUP00000014016	Uncharacterized protein.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.870
ENPP1	CTPS2	ENSOCUP00000049040	ENSOCUP00000002373	Uncharacterized protein.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.866
ENPP1	ENPP3	ENSOCUP00000049040	ENSOCUP00000012418	Uncharacterized protein.	Ectonucleotide pyrophosphatase/phosphodiesterase 3.	0.851
ENPP1	NME1	ENSOCUP00000049040	ENSOCUP00000025502	Uncharacterized protein.	Nucleoside diphosphate kinase.	0.898
ENPP1	NME6	ENSOCUP00000049040	ENSOCUP00000000478	Uncharacterized protein.	Nucleoside diphosphate kinase.	0.856
ENPP1	NUDT12	ENSOCUP00000049040	ENSOCUP00000015142	Uncharacterized protein.	Nudix hydrolase 12.	0.861