TYRO3 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

TYRO3

TYRO3 protein tyrosine kinase. (860 aa)

Predicted Functional Partners:

PROS1

0.971

MFGE8

0.664

THBS1

0.606

TRAF6

0.561

TAB1

0.558

TLR4

0.526

CD209

0.514

CD247

0.511

GRB2

0.511

TRADD

0.510

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD209	TLR4	ENSOCUP00000009370	ENSOCUP00000001909	C-type lectin domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.487
CD209	TYRO3	ENSOCUP00000009370	ENSOCUP00000005395	C-type lectin domain-containing protein.	TYRO3 protein tyrosine kinase.	0.514
CD247	GRB2	ENSOCUP00000027572	ENSOCUP00000042433	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Growth factor receptor bound protein 2.	0.601
CD247	TYRO3	ENSOCUP00000027572	ENSOCUP00000005395	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	TYRO3 protein tyrosine kinase.	0.511
GRB2	CD247	ENSOCUP00000042433	ENSOCUP00000027572	Growth factor receptor bound protein 2.	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	0.601
GRB2	TYRO3	ENSOCUP00000042433	ENSOCUP00000005395	Growth factor receptor bound protein 2.	TYRO3 protein tyrosine kinase.	0.511
MFGE8	TYRO3	ENSOCUP00000011412	ENSOCUP00000005395	Uncharacterized protein.	TYRO3 protein tyrosine kinase.	0.664
PROS1	TYRO3	ENSOCUP00000018723	ENSOCUP00000005395	Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.	TYRO3 protein tyrosine kinase.	0.971
TAB1	TLR4	ENSOCUP00000015798	ENSOCUP00000001909	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.744
TAB1	TRADD	ENSOCUP00000015798	ENSOCUP00000018718	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	TNFRSF1A associated via death domain.	0.971
TAB1	TRAF6	ENSOCUP00000015798	ENSOCUP00000026781	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
TAB1	TYRO3	ENSOCUP00000015798	ENSOCUP00000005395	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	TYRO3 protein tyrosine kinase.	0.558
THBS1	TLR4	ENSOCUP00000003290	ENSOCUP00000001909	Thrombospondin 1.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.405
THBS1	TYRO3	ENSOCUP00000003290	ENSOCUP00000005395	Thrombospondin 1.	TYRO3 protein tyrosine kinase.	0.606
TLR4	CD209	ENSOCUP00000001909	ENSOCUP00000009370	TIR domain-containing protein; Belongs to the Toll-like receptor family.	C-type lectin domain-containing protein.	0.487
TLR4	TAB1	ENSOCUP00000001909	ENSOCUP00000015798	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.744
TLR4	THBS1	ENSOCUP00000001909	ENSOCUP00000003290	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Thrombospondin 1.	0.405
TLR4	TRADD	ENSOCUP00000001909	ENSOCUP00000018718	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TNFRSF1A associated via death domain.	0.474
TLR4	TRAF6	ENSOCUP00000001909	ENSOCUP00000026781	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
TLR4	TYRO3	ENSOCUP00000001909	ENSOCUP00000005395	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TYRO3 protein tyrosine kinase.	0.526