NR5A2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

NR5A2

Uncharacterized protein. (541 aa)

Predicted Functional Partners:

NR0B1

0.938

NR0B2

0.876

NCOA2

0.803

NCOA3

0.692

CYP7A1

0.691

PPARGC1A

0.691

PRKACB

0.681

SOX9

0.679

UBE2I

0.651

KLF4

0.647

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP7A1	NR0B2	ENSOCUP00000010572	ENSOCUP00000005546	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	Nuclear receptor subfamily 0 group B member 2.	0.831
CYP7A1	NR5A2	ENSOCUP00000010572	ENSOCUP00000005400	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	Uncharacterized protein.	0.691
CYP7A1	PPARGC1A	ENSOCUP00000010572	ENSOCUP00000034883	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	PPARG coactivator 1 alpha.	0.452
KLF4	NCOA3	ENSOCUP00000005117	ENSOCUP00000037443	Uncharacterized protein.	Nuclear receptor coactivator.	0.415
KLF4	NR0B1	ENSOCUP00000005117	ENSOCUP00000000025	Uncharacterized protein.	Nuclear receptor subfamily 0 group B member 1.	0.526
KLF4	NR5A2	ENSOCUP00000005117	ENSOCUP00000005400	Uncharacterized protein.	Uncharacterized protein.	0.647
KLF4	SOX9	ENSOCUP00000005117	ENSOCUP00000010009	Uncharacterized protein.	SRY-box transcription factor 9.	0.669
NCOA2	NCOA3	ENSOCUP00000005169	ENSOCUP00000037443	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.969
NCOA2	NR5A2	ENSOCUP00000005169	ENSOCUP00000005400	Nuclear receptor coactivator.	Uncharacterized protein.	0.803
NCOA2	PPARGC1A	ENSOCUP00000005169	ENSOCUP00000034883	Nuclear receptor coactivator.	PPARG coactivator 1 alpha.	0.750
NCOA2	PRKACB	ENSOCUP00000005169	ENSOCUP00000043583	Nuclear receptor coactivator.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.671
NCOA3	KLF4	ENSOCUP00000037443	ENSOCUP00000005117	Nuclear receptor coactivator.	Uncharacterized protein.	0.415
NCOA3	NCOA2	ENSOCUP00000037443	ENSOCUP00000005169	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.969
NCOA3	NR0B2	ENSOCUP00000037443	ENSOCUP00000005546	Nuclear receptor coactivator.	Nuclear receptor subfamily 0 group B member 2.	0.415
NCOA3	NR5A2	ENSOCUP00000037443	ENSOCUP00000005400	Nuclear receptor coactivator.	Uncharacterized protein.	0.692
NCOA3	PPARGC1A	ENSOCUP00000037443	ENSOCUP00000034883	Nuclear receptor coactivator.	PPARG coactivator 1 alpha.	0.708
NCOA3	PRKACB	ENSOCUP00000037443	ENSOCUP00000043583	Nuclear receptor coactivator.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.861
NR0B1	KLF4	ENSOCUP00000000025	ENSOCUP00000005117	Nuclear receptor subfamily 0 group B member 1.	Uncharacterized protein.	0.526
NR0B1	NR5A2	ENSOCUP00000000025	ENSOCUP00000005400	Nuclear receptor subfamily 0 group B member 1.	Uncharacterized protein.	0.938
NR0B1	SOX9	ENSOCUP00000000025	ENSOCUP00000010009	Nuclear receptor subfamily 0 group B member 1.	SRY-box transcription factor 9.	0.437