HCST protein (Oryctolagus cuniculus) - STRING interaction network

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Score

HCST

Hematopoietic cell signal transducer. (92 aa)

Predicted Functional Partners:

KLRK1

0.910

TYROBP

0.876

FCER1G

0.690

CLEC5A

0.625

VAV1

0.588

GRB2

0.585

RAET1E

0.582

SYK

0.574

CD247

0.571

CD79B

0.563

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD247	CD79B	ENSOCUP00000027572	ENSOCUP00000033012	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	CD79b molecule.	0.562
CD247	FCER1G	ENSOCUP00000027572	ENSOCUP00000033471	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Fc fragment of IgE receptor Ig.	0.699
CD247	GRB2	ENSOCUP00000027572	ENSOCUP00000042433	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Growth factor receptor bound protein 2.	0.601
CD247	HCST	ENSOCUP00000027572	ENSOCUP00000005432	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Hematopoietic cell signal transducer.	0.571
CD247	KLRK1	ENSOCUP00000027572	ENSOCUP00000016073	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Killer cell lectin like receptor K1.	0.611
CD247	SYK	ENSOCUP00000027572	ENSOCUP00000015068	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Tyrosine-protein kinase.	0.996
CD247	TYROBP	ENSOCUP00000027572	ENSOCUP00000022343	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	TYRO protein tyrosine kinase binding protein.	0.609
CD247	VAV1	ENSOCUP00000027572	ENSOCUP00000022704	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Vav guanine nucleotide exchange factor 1.	0.601
CD79B	CD247	ENSOCUP00000033012	ENSOCUP00000027572	CD79b molecule.	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	0.562
CD79B	GRB2	ENSOCUP00000033012	ENSOCUP00000042433	CD79b molecule.	Growth factor receptor bound protein 2.	0.621
CD79B	HCST	ENSOCUP00000033012	ENSOCUP00000005432	CD79b molecule.	Hematopoietic cell signal transducer.	0.563
CD79B	SYK	ENSOCUP00000033012	ENSOCUP00000015068	CD79b molecule.	Tyrosine-protein kinase.	0.955
CD79B	VAV1	ENSOCUP00000033012	ENSOCUP00000022704	CD79b molecule.	Vav guanine nucleotide exchange factor 1.	0.550
CLEC5A	FCER1G	ENSOCUP00000008259	ENSOCUP00000033471	C-type lectin domain containing 5A.	Fc fragment of IgE receptor Ig.	0.600
CLEC5A	HCST	ENSOCUP00000008259	ENSOCUP00000005432	C-type lectin domain containing 5A.	Hematopoietic cell signal transducer.	0.625
CLEC5A	SYK	ENSOCUP00000008259	ENSOCUP00000015068	C-type lectin domain containing 5A.	Tyrosine-protein kinase.	0.744
CLEC5A	TYROBP	ENSOCUP00000008259	ENSOCUP00000022343	C-type lectin domain containing 5A.	TYRO protein tyrosine kinase binding protein.	0.872
FCER1G	CD247	ENSOCUP00000033471	ENSOCUP00000027572	Fc fragment of IgE receptor Ig.	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	0.699
FCER1G	CLEC5A	ENSOCUP00000033471	ENSOCUP00000008259	Fc fragment of IgE receptor Ig.	C-type lectin domain containing 5A.	0.600
FCER1G	HCST	ENSOCUP00000033471	ENSOCUP00000005432	Fc fragment of IgE receptor Ig.	Hematopoietic cell signal transducer.	0.690