RFFL protein (Oryctolagus cuniculus) - STRING interaction network

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RFFL

Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (361 aa)

Predicted Functional Partners:

UBE2D2

0.820

RNF34

0.773

EFCAB7

0.751

DNAJB14

0.715

DNAJB12

0.697

MYRF

0.683

PRRG1

0.672

TP53

0.652

G1U940_RABIT

0.652

RNF207

0.637

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAJB12	RFFL	ENSOCUP00000014952	ENSOCUP00000005459	DnaJ heat shock protein family (Hsp40) member B12.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.697
DNAJB14	RFFL	ENSOCUP00000005662	ENSOCUP00000005459	DnaJ heat shock protein family (Hsp40) member B14.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.715
EFCAB7	RFFL	ENSOCUP00000000252	ENSOCUP00000005459	EF-hand calcium binding domain 7.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.751
EFCAB7	RNF34	ENSOCUP00000000252	ENSOCUP00000032052	EF-hand calcium binding domain 7.	Ring finger protein 34.	0.594
G1U940_RABIT	RFFL	ENSOCUP00000025959	ENSOCUP00000005459	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.652
G1U940_RABIT	RNF34	ENSOCUP00000025959	ENSOCUP00000032052	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ring finger protein 34.	0.526
MYRF	RFFL	ENSOCUP00000040110	ENSOCUP00000005459	Myelin regulatory factor.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.683
PRRG1	RFFL	ENSOCUP00000013284	ENSOCUP00000005459	Proline rich and Gla domain 1.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.672
RFFL	DNAJB12	ENSOCUP00000005459	ENSOCUP00000014952	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	DnaJ heat shock protein family (Hsp40) member B12.	0.697
RFFL	DNAJB14	ENSOCUP00000005459	ENSOCUP00000005662	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	DnaJ heat shock protein family (Hsp40) member B14.	0.715
RFFL	EFCAB7	ENSOCUP00000005459	ENSOCUP00000000252	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	EF-hand calcium binding domain 7.	0.751
RFFL	G1U940_RABIT	ENSOCUP00000005459	ENSOCUP00000025959	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.652
RFFL	MYRF	ENSOCUP00000005459	ENSOCUP00000040110	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	Myelin regulatory factor.	0.683
RFFL	PRRG1	ENSOCUP00000005459	ENSOCUP00000013284	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	Proline rich and Gla domain 1.	0.672
RFFL	RNF207	ENSOCUP00000005459	ENSOCUP00000032469	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.	0.637
RFFL	RNF34	ENSOCUP00000005459	ENSOCUP00000032052	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	Ring finger protein 34.	0.773
RFFL	TP53	ENSOCUP00000005459	ENSOCUP00000000989	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.652
RFFL	UBE2D2	ENSOCUP00000005459	ENSOCUP00000026812	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.820
RNF207	RFFL	ENSOCUP00000032469	ENSOCUP00000005459	RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.637
RNF34	EFCAB7	ENSOCUP00000032052	ENSOCUP00000000252	Ring finger protein 34.	EF-hand calcium binding domain 7.	0.594