Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSKH1Protein serine kinase H1; Belongs to the protein kinase superfamily. (424 aa)    
Predicted Functional Partners:
DCX
Doublecortin.
 
 
 
 0.858
TTN
Uncharacterized protein.
 
  
 0.749
ENSOCUP00000030887
Uncharacterized protein.
 
  
 0.741
MPP1
Palmitoylated membrane protein 1 (Predicted); Belongs to the MAGUK family.
 
 
  0.607
EDC4
Enhancer of mRNA decapping 4.
   
  
 0.502
SLC12A4
Solute carrier family 12 member 4; Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia; Belongs to the SLC12A transporter family.
   
 
 0.495
LCAT
Phosphatidylcholine-sterol acyltransferase; Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE- containing lipoproteins secreted from glia and influences cerebral spinal [...]
      
 0.490
RIPOR1
RHO family interacting cell polarization regulator 1.
      
 0.481
SLC12A2
Solute carrier family 12 member 2.
   
 
 0.474
RNF17
Ring finger protein 17.
     
 0.472
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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