Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNOCyclin O; Belongs to the cyclin family. (514 aa)    
Predicted Functional Partners:
CDC20B
Cell division cycle 20B.
   
 0.929
MCIDAS
Multiciliate differentiation and DNA synthesis associated cell cycle protein.
   
  
 0.902
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.796
DEUP1
Deuterosome assembly protein 1.
    
 
 0.777
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
   
 0.774
CDKN1A
Uncharacterized protein.
    
 0.759
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.753
FOXJ1
Forkhead box J1.
   
 0.752
PLK4
Polo like kinase 4.
   
 0.733
RSPH4A
Radial spoke head component 4A.
    
 0.730
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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