STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFATC1RHD domain-containing protein. (672 aa)    
Predicted Functional Partners:
PPP3CA
Serine/threonine-protein phosphatase.
    
 0.996
PPP3CB
Serine/threonine-protein phosphatase.
    
 0.978
PPP3CC
Serine/threonine-protein phosphatase.
    
 0.976
NFATC2
Nuclear factor of activated T cells 2.
   
0.971
NFATC3
Nuclear factor of activated T cells 3.
   
 
0.960
MAPK9
Mitogen-activated protein kinase.
    
 0.952
MAPK10
Mitogen-activated protein kinase.
    
 0.948
MAPK8
Mitogen-activated protein kinase.
    
 0.948
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
   
 0.948
CTSK
Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family.
   
  
 0.946
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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