| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARR3 | ENSOCUP00000039917 | ENSOCUP00000014674 | ENSOCUP00000039917 | Arrestin 3. | RGS domain-containing protein. | 0.781 |
| ARR3 | GNB1 | ENSOCUP00000014674 | ENSOCUP00000008676 | Arrestin 3. | G protein subunit beta 1. | 0.578 |
| ARR3 | GNB4 | ENSOCUP00000014674 | ENSOCUP00000000803 | Arrestin 3. | G protein subunit beta 4. | 0.578 |
| ARR3 | GRK3 | ENSOCUP00000014674 | ENSOCUP00000022116 | Arrestin 3. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.781 |
| ARR3 | LOC100346604 | ENSOCUP00000014674 | ENSOCUP00000005641 | Arrestin 3. | Olfactory receptor. | 0.422 |
| ARRB1 | ENSOCUP00000039917 | ENSOCUP00000019641 | ENSOCUP00000039917 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | RGS domain-containing protein. | 0.893 |
| ARRB1 | GNB1 | ENSOCUP00000019641 | ENSOCUP00000008676 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | G protein subunit beta 1. | 0.691 |
| ARRB1 | GNB4 | ENSOCUP00000019641 | ENSOCUP00000000803 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | G protein subunit beta 4. | 0.691 |
| ARRB1 | GRK3 | ENSOCUP00000019641 | ENSOCUP00000022116 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.918 |
| ARRB1 | LOC100346604 | ENSOCUP00000019641 | ENSOCUP00000005641 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Olfactory receptor. | 0.575 |
| ARRB1 | PRKACB | ENSOCUP00000019641 | ENSOCUP00000043583 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.594 |
| ENSOCUP00000035103 | ENSOCUP00000039917 | ENSOCUP00000035103 | ENSOCUP00000039917 | G protein gamma domain-containing protein. | RGS domain-containing protein. | 0.424 |
| ENSOCUP00000035103 | GNAL | ENSOCUP00000035103 | ENSOCUP00000004556 | G protein gamma domain-containing protein. | G protein subunit alpha L. | 0.972 |
| ENSOCUP00000035103 | GNB1 | ENSOCUP00000035103 | ENSOCUP00000008676 | G protein gamma domain-containing protein. | G protein subunit beta 1. | 0.961 |
| ENSOCUP00000035103 | GNB4 | ENSOCUP00000035103 | ENSOCUP00000000803 | G protein gamma domain-containing protein. | G protein subunit beta 4. | 0.961 |
| ENSOCUP00000035103 | GRK3 | ENSOCUP00000035103 | ENSOCUP00000022116 | G protein gamma domain-containing protein. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.424 |
| ENSOCUP00000035103 | LOC100346604 | ENSOCUP00000035103 | ENSOCUP00000005641 | G protein gamma domain-containing protein. | Olfactory receptor. | 0.543 |
| ENSOCUP00000035103 | PRKACB | ENSOCUP00000035103 | ENSOCUP00000043583 | G protein gamma domain-containing protein. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.863 |
| ENSOCUP00000039917 | ARR3 | ENSOCUP00000039917 | ENSOCUP00000014674 | RGS domain-containing protein. | Arrestin 3. | 0.781 |
| ENSOCUP00000039917 | ARRB1 | ENSOCUP00000039917 | ENSOCUP00000019641 | RGS domain-containing protein. | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | 0.893 |
