STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1157 aa)    
Predicted Functional Partners:
GNAT3
G protein subunit alpha transducin 3.
   
 0.990
GNA14
G protein subunit alpha 14.
    
 0.975
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
   
 0.970
GNAQ
G protein subunit alpha q.
    
 0.967
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
   
 0.957
GNB3
G protein subunit beta 3.
     
 0.956
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
  
  
0.949
GNAI1
G protein subunit alpha i1.
   
 0.944
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
   
 0.943
GPRC6A
G protein-coupled receptor class C group 6 member A.
     
 0.942
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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