STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EXD2Exonuclease 3'-5' domain containing 2. (643 aa)    
Predicted Functional Partners:
DNA2
DNA replication helicase/nuclease 2.
   
 
 0.907
EXO1
Exonuclease 1.
   
 0.902
RPA3
Replication protein A3.
    
  0.834
EXD1
Exonuclease 3'-5' domain containing 1.
   
  
 0.779
XRCC6
X-ray repair cross complementing 6.
    
 
 0.734
MEIOB
Meiosis specific with OB-fold.
    
 0.714
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.714
XRCC5
X-ray repair cross complementing 5.
    
 
 0.704
SLF1
SMC5-SMC6 complex localization factor 1.
   
 
 0.689
WRNIP1
WRN helicase interacting protein 1.
    
 
 0.680
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.