STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETF1Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. (437 aa)    
Predicted Functional Partners:
ABCE1
Uncharacterized protein.
   
 
 0.990
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
   
 
 0.989
GSPT2
G1 to S phase transition 2.
   
 0.978
GSPT1
G1 to S phase transition 1.
   
 0.978
ENSOCUP00000043653
ABC transporter domain-containing protein.
   
 
 0.965
G1U1Y5_RABIT
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.951
FAU
Ubiquitin-like domain-containing protein.
   
 0.951
ENSOCUP00000046875
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.951
ENSOCUP00000049185
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.951
N6AMT1
N-6 adenine-specific DNA methyltransferase 1.
    
 0.891
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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