Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HEXIM2HEXIM P-TEFb complex subunit 2. (302 aa)    
Predicted Functional Partners:
LARP7
La ribonucleoprotein domain family member 7.
    
 
 0.973
MEPCE
Methylphosphate capping enzyme.
   
 
 0.972
CCNT1
Cyclin T1; Belongs to the cyclin family.
    
 
 0.954
CCNT2
Cyclin T2.
    
 
 0.917
AFF4
Uncharacterized protein RA_m002_jsmFBA6Br.
    
 
 0.865
G1T4I8_RABIT
Uncharacterized protein.
   
 
 0.817
CCNK
Cyclin K; Belongs to the cyclin family.
    
 
 0.733
AFF1
AF4/FMR2 family member 1.
    
 
 0.707
DDX21
DExD-box helicase 21.
    
 
 0.658
AP2A1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
   0.611
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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