| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQP2 | AQP3 | ENSOCUP00000047709 | ENSOCUP00000015333 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.688 |
| AQP2 | SLC12A1 | ENSOCUP00000047709 | ENSOCUP00000014189 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. Belongs to the SLC12A transporter family. | 0.885 |
| AQP2 | SLC14A1 | ENSOCUP00000047709 | ENSOCUP00000005841 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Urea transporter; Belongs to the urea transporter family. | 0.763 |
| AQP3 | AQP2 | ENSOCUP00000015333 | ENSOCUP00000047709 | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.688 |
| AQP3 | SLC12A1 | ENSOCUP00000015333 | ENSOCUP00000014189 | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. Belongs to the SLC12A transporter family. | 0.558 |
| AQP3 | SLC14A1 | ENSOCUP00000015333 | ENSOCUP00000005841 | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. | Urea transporter; Belongs to the urea transporter family. | 0.689 |
| ATP6V0D1 | ATP6V1F | ENSOCUP00000010186 | ENSOCUP00000012144 | ATPase H+ transporting V0 subunit d1. | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.983 |
| ATP6V0D1 | SLC14A1 | ENSOCUP00000010186 | ENSOCUP00000005841 | ATPase H+ transporting V0 subunit d1. | Urea transporter; Belongs to the urea transporter family. | 0.691 |
| ATP6V0D2 | ATP6V1F | ENSOCUP00000008836 | ENSOCUP00000012144 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.964 |
| ATP6V0D2 | SLC14A1 | ENSOCUP00000008836 | ENSOCUP00000005841 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. | Urea transporter; Belongs to the urea transporter family. | 0.691 |
| ATP6V1F | ATP6V0D1 | ENSOCUP00000012144 | ENSOCUP00000010186 | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | ATPase H+ transporting V0 subunit d1. | 0.983 |
| ATP6V1F | ATP6V0D2 | ENSOCUP00000012144 | ENSOCUP00000008836 | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. | 0.964 |
| ATP6V1F | SLC14A1 | ENSOCUP00000012144 | ENSOCUP00000005841 | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | Urea transporter; Belongs to the urea transporter family. | 0.594 |
| GSK3B | PPARGC1A | ENSOCUP00000034516 | ENSOCUP00000034883 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | PPARG coactivator 1 alpha. | 0.453 |
| GSK3B | RBBP5 | ENSOCUP00000034516 | ENSOCUP00000037943 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | RB binding protein 5, histone lysine methyltransferase complex subunit. | 0.565 |
| GSK3B | SLC14A1 | ENSOCUP00000034516 | ENSOCUP00000005841 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Urea transporter; Belongs to the urea transporter family. | 0.560 |
| GSK3B | WDR82 | ENSOCUP00000034516 | ENSOCUP00000007400 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | WD repeat domain 82. | 0.570 |
| PPARGC1A | GSK3B | ENSOCUP00000034883 | ENSOCUP00000034516 | PPARG coactivator 1 alpha. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.453 |
| PPARGC1A | RBBP5 | ENSOCUP00000034883 | ENSOCUP00000037943 | PPARG coactivator 1 alpha. | RB binding protein 5, histone lysine methyltransferase complex subunit. | 0.560 |
| PPARGC1A | SLC14A1 | ENSOCUP00000034883 | ENSOCUP00000005841 | PPARG coactivator 1 alpha. | Urea transporter; Belongs to the urea transporter family. | 0.560 |