OPTN protein (Oryctolagus cuniculus) - STRING interaction network

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Predicted Interactions

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Score

OPTN

Optineurin. (521 aa)

Predicted Functional Partners:

TBK1

0.963

GABARAP

0.915

TMEM52B

0.915

GABARAPL2

0.911

TANK

0.904

IKBKB

0.880

CHUK

0.880

CYLD

0.710

CALCOCO2

0.599

RAB8B

0.589

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALCOCO2	GABARAP	ENSOCUP00000026662	ENSOCUP00000006049	Calcium binding and coiled-coil domain 2.	Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family.	0.459
CALCOCO2	GABARAPL2	ENSOCUP00000026662	ENSOCUP00000014267	Calcium binding and coiled-coil domain 2.	GABA type A receptor associated protein like 2.	0.685
CALCOCO2	OPTN	ENSOCUP00000026662	ENSOCUP00000005877	Calcium binding and coiled-coil domain 2.	Optineurin.	0.599
CALCOCO2	TBK1	ENSOCUP00000026662	ENSOCUP00000035620	Calcium binding and coiled-coil domain 2.	TANK binding kinase 1.	0.847
CALCOCO2	TMEM52B	ENSOCUP00000026662	ENSOCUP00000014468	Calcium binding and coiled-coil domain 2.	Uncharacterized protein.	0.657
CHUK	CYLD	ENSOCUP00000031319	ENSOCUP00000032691	Component of inhibitor of nuclear factor kappa B kinase complex.	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.	0.787
CHUK	IKBKB	ENSOCUP00000031319	ENSOCUP00000006175	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.999
CHUK	OPTN	ENSOCUP00000031319	ENSOCUP00000005877	Component of inhibitor of nuclear factor kappa B kinase complex.	Optineurin.	0.880
CHUK	TANK	ENSOCUP00000031319	ENSOCUP00000018640	Component of inhibitor of nuclear factor kappa B kinase complex.	TRAF family member associated NFKB activator.	0.626
CHUK	TBK1	ENSOCUP00000031319	ENSOCUP00000035620	Component of inhibitor of nuclear factor kappa B kinase complex.	TANK binding kinase 1.	0.660
CYLD	CHUK	ENSOCUP00000032691	ENSOCUP00000031319	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.787
CYLD	IKBKB	ENSOCUP00000032691	ENSOCUP00000006175	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.698
CYLD	OPTN	ENSOCUP00000032691	ENSOCUP00000005877	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.	Optineurin.	0.710
CYLD	TANK	ENSOCUP00000032691	ENSOCUP00000018640	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.	TRAF family member associated NFKB activator.	0.511
CYLD	TBK1	ENSOCUP00000032691	ENSOCUP00000035620	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.	TANK binding kinase 1.	0.901
GABARAP	CALCOCO2	ENSOCUP00000006049	ENSOCUP00000026662	Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family.	Calcium binding and coiled-coil domain 2.	0.459
GABARAP	GABARAPL2	ENSOCUP00000006049	ENSOCUP00000014267	Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family.	GABA type A receptor associated protein like 2.	0.945
GABARAP	OPTN	ENSOCUP00000006049	ENSOCUP00000005877	Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family.	Optineurin.	0.915
GABARAP	TMEM52B	ENSOCUP00000006049	ENSOCUP00000014468	Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family.	Uncharacterized protein.	0.902
GABARAPL2	CALCOCO2	ENSOCUP00000014267	ENSOCUP00000026662	GABA type A receptor associated protein like 2.	Calcium binding and coiled-coil domain 2.	0.685