Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
HORMAD2HORMA domain containing 2. (306 aa)    
Predicted Functional Partners:
SPO11
SPO11 initiator of meiotic double stranded breaks.
   
  
 0.892
TRIP13
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 
 0.872
DMC1
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
   
 
 0.849
SYCP3
Synaptonemal complex protein 3.
   
 
 0.838
MSH4
MutS homolog 4.
   
  
 0.826
TERB1
Telomere repeat binding bouquet formation protein 1.
      
 0.778
REC8
REC8 meiotic recombination protein.
   
 
 0.778
MEI1
Meiotic double-stranded break formation protein 1.
      
 0.775
SYCE3
Synaptonemal complex central element protein 3.
      
 0.739
REC114
REC114 meiotic recombination protein.
      
 0.729
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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