STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPFFR2Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family. (415 aa)    
Predicted Functional Partners:
NPFF
Neuropeptide FF-amide peptide precursor.
     
 0.977
NPFFR1
Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
0.940
NPVF
Neuropeptide VF precursor.
   
  
 0.780
SAG
S-antigen visual arrestin.
   
 0.527
ARR3
Arrestin 3.
   
 0.527
ARRB1
Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]
   
 0.527
TTC21B
Tetratricopeptide repeat domain 21B.
     
 0.522
RCVRN
Recoverin.
   
 0.505
GNAO1
G protein subunit alpha o1.
   
 0.499
GNB4
G protein subunit beta 4.
    
 0.498
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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