PPP4R3B protein (Oryctolagus cuniculus) - STRING interaction network

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Score

PPP4R3B

Protein phosphatase 4 regulatory subunit 3B. (806 aa)

Predicted Functional Partners:

PPP4C

0.988

PPP4R3A

0.959

CRTC2

0.922

PPP4R2

0.898

G1TK57_RABIT

0.814

ENSOCUP00000027254

0.814

PTPA

0.812

PPP4R1

0.800

PPP1R21

0.653

DOP1A

0.650

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRTC2	PPP4C	ENSOCUP00000013514	ENSOCUP00000005480	CREB regulated transcription coactivator 2.	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	0.914
CRTC2	PPP4R3A	ENSOCUP00000013514	ENSOCUP00000015262	CREB regulated transcription coactivator 2.	Protein phosphatase 4 regulatory subunit 3A.	0.920
CRTC2	PPP4R3B	ENSOCUP00000013514	ENSOCUP00000005953	CREB regulated transcription coactivator 2.	Protein phosphatase 4 regulatory subunit 3B.	0.922
DOP1A	PPP4R3B	ENSOCUP00000009283	ENSOCUP00000005953	DOP1 leucine zipper like protein A.	Protein phosphatase 4 regulatory subunit 3B.	0.650
ENSOCUP00000027254	PPP4C	ENSOCUP00000027254	ENSOCUP00000005480	Uncharacterized protein.	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	0.949
ENSOCUP00000027254	PPP4R1	ENSOCUP00000027254	ENSOCUP00000029628	Uncharacterized protein.	Protein phosphatase 4 regulatory subunit 1.	0.584
ENSOCUP00000027254	PPP4R3A	ENSOCUP00000027254	ENSOCUP00000015262	Uncharacterized protein.	Protein phosphatase 4 regulatory subunit 3A.	0.825
ENSOCUP00000027254	PPP4R3B	ENSOCUP00000027254	ENSOCUP00000005953	Uncharacterized protein.	Protein phosphatase 4 regulatory subunit 3B.	0.814
ENSOCUP00000027254	PTPA	ENSOCUP00000027254	ENSOCUP00000044909	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyr [...]	0.806
G1TK57_RABIT	PPP4C	ENSOCUP00000017340	ENSOCUP00000005480	Uncharacterized protein.	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	0.949
G1TK57_RABIT	PPP4R1	ENSOCUP00000017340	ENSOCUP00000029628	Uncharacterized protein.	Protein phosphatase 4 regulatory subunit 1.	0.584
G1TK57_RABIT	PPP4R3A	ENSOCUP00000017340	ENSOCUP00000015262	Uncharacterized protein.	Protein phosphatase 4 regulatory subunit 3A.	0.825
G1TK57_RABIT	PPP4R3B	ENSOCUP00000017340	ENSOCUP00000005953	Uncharacterized protein.	Protein phosphatase 4 regulatory subunit 3B.	0.814
G1TK57_RABIT	PTPA	ENSOCUP00000017340	ENSOCUP00000044909	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyr [...]	0.806
PPP1R21	PPP4R3B	ENSOCUP00000030491	ENSOCUP00000005953	Protein phosphatase 1 regulatory subunit 21.	Protein phosphatase 4 regulatory subunit 3B.	0.653
PPP4C	CRTC2	ENSOCUP00000005480	ENSOCUP00000013514	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	CREB regulated transcription coactivator 2.	0.914
PPP4C	ENSOCUP00000027254	ENSOCUP00000005480	ENSOCUP00000027254	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Uncharacterized protein.	0.949
PPP4C	G1TK57_RABIT	ENSOCUP00000005480	ENSOCUP00000017340	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Uncharacterized protein.	0.949
PPP4C	PPP4R1	ENSOCUP00000005480	ENSOCUP00000029628	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Protein phosphatase 4 regulatory subunit 1.	0.933
PPP4C	PPP4R2	ENSOCUP00000005480	ENSOCUP00000005396	Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...]	Serine/threonine-protein phosphatase 4 regulatory subunit 2.	0.985