KRT8 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

KRT8

Keratin 8; Belongs to the intermediate filament family. (486 aa)

Predicted Functional Partners:

KRT18

0.992

LOC100008885

0.893

UBE2V1

0.824

BAG3

0.714

EGFR

0.614

DSP

0.596

CLDN4

0.588

ERBB2

0.585

TP53

0.572

ESR1

0.554

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG3	EGFR	ENSOCUP00000010054	ENSOCUP00000009041	BCL2 associated athanogene 3.	Receptor protein-tyrosine kinase.	0.434
BAG3	KRT8	ENSOCUP00000010054	ENSOCUP00000006005	BCL2 associated athanogene 3.	Keratin 8; Belongs to the intermediate filament family.	0.714
BAG3	TP53	ENSOCUP00000010054	ENSOCUP00000000989	BCL2 associated athanogene 3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.533
CLDN4	EGFR	ENSOCUP00000008921	ENSOCUP00000009041	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Receptor protein-tyrosine kinase.	0.411
CLDN4	KRT18	ENSOCUP00000008921	ENSOCUP00000025258	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.509
CLDN4	KRT8	ENSOCUP00000008921	ENSOCUP00000006005	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Keratin 8; Belongs to the intermediate filament family.	0.588
DSP	KRT18	ENSOCUP00000011336	ENSOCUP00000025258	Desmoplakin.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.689
DSP	KRT8	ENSOCUP00000011336	ENSOCUP00000006005	Desmoplakin.	Keratin 8; Belongs to the intermediate filament family.	0.596
DSP	LOC100008885	ENSOCUP00000011336	ENSOCUP00000018252	Desmoplakin.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.491
EGFR	BAG3	ENSOCUP00000009041	ENSOCUP00000010054	Receptor protein-tyrosine kinase.	BCL2 associated athanogene 3.	0.434
EGFR	CLDN4	ENSOCUP00000009041	ENSOCUP00000008921	Receptor protein-tyrosine kinase.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.411
EGFR	ERBB2	ENSOCUP00000009041	ENSOCUP00000009117	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
EGFR	ESR1	ENSOCUP00000009041	ENSOCUP00000004174	Receptor protein-tyrosine kinase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.959
EGFR	KRT18	ENSOCUP00000009041	ENSOCUP00000025258	Receptor protein-tyrosine kinase.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.444
EGFR	KRT8	ENSOCUP00000009041	ENSOCUP00000006005	Receptor protein-tyrosine kinase.	Keratin 8; Belongs to the intermediate filament family.	0.614
EGFR	TP53	ENSOCUP00000009041	ENSOCUP00000000989	Receptor protein-tyrosine kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.871
ERBB2	EGFR	ENSOCUP00000009117	ENSOCUP00000009041	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
ERBB2	ESR1	ENSOCUP00000009117	ENSOCUP00000004174	Receptor protein-tyrosine kinase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.927
ERBB2	KRT8	ENSOCUP00000009117	ENSOCUP00000006005	Receptor protein-tyrosine kinase.	Keratin 8; Belongs to the intermediate filament family.	0.585
ERBB2	TP53	ENSOCUP00000009117	ENSOCUP00000000989	Receptor protein-tyrosine kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.798